Focusing on diseases related to cellular energy metabolism such as cancer and diabetes analysis of complex diseases a mathematical perspective presents a holistic approach for illuminating the molecular mechanisms of these diseases and the evolutionary underpinning of their simultaneous epidemics using mathematics to identify patterns of . Request pdf analysis of complex diseases a mathematical perspective a complex disease involves many etiological and risk factors operating at multiple levels molecular cellular organismal . A complex disease involves many etiological and risk factors operating at multiple levels molecular cellular organismal and environmental the incidence of such diseases as cancer obesity and diabetes are increasing in occurrence urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize trea. Focusing on diseases related to cellular energy metabolism such as cancer and diabetes analysis of complex diseases a mathematical perspective presents a holistic approach for illuminating the molecular mechanisms of these diseases and the evolutionary underpinning of their simultaneous epidemics